Mesothelioma
Mesothelioma is a rare but aggressive cancer caused almost exclusively by exposure to asbestos fibers. This disease develops in the mesothelium, a thin layer of tissue that lines various organs, most commonly the lungs (pleural mesothelioma), abdomen (peritoneal mesothelioma), or heart (pericardial mesothelioma). While asbestos use peaked in the 20th century, mesothelioma cases continue to rise due to the disease’s long latency period, which can extend 20 to 50 years after initial exposure.
The connection between asbestos and mesothelioma was first scientifically documented in 1960 through a groundbreaking study by Dr. Chris Wagner in South Africa. Wagner’s research highlighted the alarming rates of mesothelioma among workers exposed to asbestos in mining regions. This landmark study drew international attention to the severe health risks of asbestos exposure and laid the foundation for modern understanding and regulation. Learn more about Wagner’s study.
Although mesothelioma remains a challenging disease to treat, advances in medical care have improved quality of life and extended survival times for many patients. Early diagnosis, cutting-edge treatments, and support from experienced medical and legal professionals can make a significant difference. This page provides a comprehensive overview of mesothelioma, including its types, symptoms, diagnosis, and treatment options, as well as the legal resources available for those affected.
Types of Mesothelioma
Mesothelioma can develop in different parts of the body, depending on where asbestos fibers settle and cause cellular damage. While asbestos fibers are most commonly inhaled, they can travel through the body in ways that many people don’t realize. After inhalation or ingestion, these microscopic fibers can lodge in the thin tissue layer called the mesothelium, which lines various organs. Over time, these fibers can cause inflammation, scarring, and mutations in the surrounding cells, ultimately leading to cancer.
There are four main types of mesothelioma, classified by the location in the body where the cancer develops:
1. Pleural Mesothelioma
Affected Area: The lining of the lungs (pleura).
Prevalence: This is the most common form of mesothelioma, accounting for 75% to 90% of all diagnosed cases.
Pleural mesothelioma occurs when asbestos fibers are inhaled and become embedded in the pleura, the protective membrane surrounding the lungs. The fibers cause chronic irritation and inflammation, which eventually leads to tumor growth. Symptoms often include shortness of breath, chest pain, persistent cough, and pleural effusions (fluid buildup in the chest cavity).
Learn more about pleural mesothelioma.
2. Peritoneal Mesothelioma
Affected Area: The lining of the abdomen (peritoneum).
Prevalence: Peritoneal mesothelioma makes up 10% to 20% of mesothelioma cases.
Asbestos fibers can also be ingested, allowing them to travel to the abdominal cavity where they settle in the peritoneum. This type of mesothelioma often causes abdominal swelling, pain, digestive issues, and unexplained weight loss. Although less common than pleural mesothelioma, peritoneal mesothelioma has seen advancements in treatment options, such as HIPEC (heated intraperitoneal chemotherapy).
Learn more about peritoneal mesothelioma.
3. Pericardial Mesothelioma
Affected Area: The lining of the heart (pericardium).
Prevalence: Pericardial mesothelioma is extremely rare, accounting for less than 1% of cases.
Although rare, asbestos fibers can travel through the bloodstream and embed in the pericardium, the protective sac around the heart. This type of mesothelioma can cause symptoms such as chest pain, irregular heartbeat, and fluid buildup around the heart (pericardial effusion). Due to its rarity, pericardial mesothelioma is challenging to diagnose and treat.
Learn more about pericardial mesothelioma.
4. Testicular Mesothelioma
Affected Area: The lining of the testes (tunica vaginalis).
Prevalence: Testicular mesothelioma is the rarest form, accounting for less than 1% of cases.
Testicular mesothelioma develops when asbestos fibers travel to the lower body, potentially through the lymphatic system, and settle in the tunica vaginalis. Symptoms are often vague and may include swelling or lumps in the scrotum. Due to its rarity, testicular mesothelioma is less studied and often diagnosed during surgery for other conditions.
Learn more about testicular mesothelioma.
Understanding the Types of Mesothelioma
Each type of mesothelioma presents unique challenges for diagnosis and treatment, but they all share a common cause: exposure to asbestos fibers. Understanding the type and location of the disease is essential for developing an effective treatment plan. To learn more about specific types of mesothelioma, click the links above for detailed information.
Histological Subtypes of Mesothelioma
Mesothelioma can also be classified by its histology, which refers to the microscopic structure of the cancer cells. The histological subtype of mesothelioma is a critical factor in determining the disease’s prognosis and treatment options. Pathologists analyze tissue samples from biopsies to classify mesothelioma into one of three main subtypes:
1. Epithelioid Mesothelioma
Description: Epithelioid mesothelioma is the most common histological subtype, accounting for approximately 70% of cases. The cells are uniform and form organized, tube-like structures, making them easier to identify and treat compared to other subtypes.
Prognosis: Epithelioid mesothelioma is associated with a better prognosis because it responds more effectively to treatments like surgery, chemotherapy, and radiation therapy.
Learn more about epithelioid mesothelioma.
2. Sarcomatoid Mesothelioma
Description: Sarcomatoid mesothelioma is the least common subtype, accounting for about 10% to 15% of cases. The cells are spindle-shaped and often overlap in a disorganized pattern, making this subtype more difficult to treat and diagnose accurately.
Prognosis: This aggressive subtype typically has a poorer prognosis due to its resistance to conventional treatments.
Learn more about sarcomatoid mesothelioma.
3. Biphasic Mesothelioma
Description: Biphasic mesothelioma contains a mixture of both epithelioid and sarcomatoid cells. The proportion of each cell type can vary significantly between cases, which affects the disease’s behavior and treatment response.
Prognosis: The prognosis for biphasic mesothelioma depends on the ratio of epithelioid to sarcomatoid cells. Cases with a higher proportion of epithelioid cells generally have a better outlook.
Learn more about biphasic mesothelioma.
Why Histology Matters
The histological subtype of mesothelioma not only influences prognosis but also guides treatment decisions. For example, patients with epithelioid mesothelioma may benefit from surgery, while sarcomatoid cases might rely more on experimental therapies due to their resistance to standard treatments.
Understanding your mesothelioma’s histology is essential for developing an effective treatment plan. Click the links above to explore each subtype in detail and learn more about their unique characteristics.
Symptoms of Mesothelioma
Mesothelioma symptoms can vary depending on the type and stage of the disease, but they often develop gradually due to the long latency period of asbestos-related conditions. Unfortunately, these symptoms are frequently mistaken for less serious illnesses, which can delay diagnosis. Recognizing the early warning signs is essential for seeking timely medical attention and improving outcomes.
General Symptoms Across All Types of Mesothelioma
Some symptoms are common across all types of mesothelioma and may indicate the disease regardless of its location.
General Symptoms:
Fatigue or general weakness.
Fever or night sweats.
Unexplained weight loss.
Symptoms of Pleural Mesothelioma (Lungs)
Pleural mesothelioma, the most common type, affects the lining of the lungs (pleura). Symptoms often relate to respiratory issues and chest discomfort.
Common Symptoms:
Persistent shortness of breath (dyspnea).
Chest pain or tightness.
Chronic dry cough.
Fatigue and general weakness.
Unexplained weight loss.
Pleural effusion (fluid buildup in the chest cavity).
Key Insight: Nearly all individuals diagnosed with pleural mesothelioma first present with pleural effusion, often accompanied by difficulty breathing or chest discomfort. Early detection of these symptoms can lead to quicker diagnosis and treatment.
Symptoms of Peritoneal Mesothelioma (Abdomen)
Peritoneal mesothelioma affects the lining of the abdominal cavity (peritoneum). Symptoms are often related to digestive and abdominal issues.
Common Symptoms:
Abdominal pain or swelling.
Nausea or vomiting.
Loss of appetite and weight loss.
Bowel obstruction or changes in bowel habits.
Ascites (fluid buildup in the abdominal cavity).
Symptoms of Pericardial Mesothelioma (Heart)
Pericardial mesothelioma is rare and affects the lining around the heart (pericardium). Symptoms are often related to heart and circulatory issues.
Common Symptoms:
Chest pain or pressure.
Irregular heartbeat (arrhythmia).
Shortness of breath.
Pericardial effusion (fluid around the heart).
Symptoms of Testicular Mesothelioma (Testes)
Testicular mesothelioma is the rarest form, affecting the lining of the testes (tunica vaginalis). Symptoms are often localized to the scrotum.
Common Symptoms:
Swelling or lumps in the scrotum.
Pain in the affected area (less common).
Fluid buildup in the scrotum (hydrocele).
For more detailed information about the symptoms of each subtype of mesothelioma, including treatment options and prognosis, visit our dedicated pages on Pleural Mesothelioma, Peritoneal Mesothelioma, Pericardial Mesothelioma, and Testicular Mesothelioma. These resources provide in-depth insights tailored to each type of the disease.
If You’re Experiencing Symptoms
If you or a family member has been exposed to asbestos and is experiencing any of these symptoms, it’s important to consult a medical professional immediately. Early diagnosis can improve treatment options and outcomes.
Our firm offers free asbestos health tests to individuals and their families, including assessments for mesothelioma symptoms. If you’re concerned about your health, contact us today to schedule a free evaluation.
Overview of Mesothelioma Treatment Options
While there is no universal cure for mesothelioma, advances in treatment have significantly improved survival times and quality of life for many patients. Treatment plans are personalized based on the type, stage, and subtype of the disease, as well as the patient’s overall health. The goal of treatment is to manage symptoms, slow disease progression, and enhance quality of life.
Here’s a simplified overview of the most common treatment options for mesothelioma:
Surgery
What It Is: Surgery aims to remove as much of the cancer as possible, especially in early-stage mesothelioma. Common procedures include:
Extrapleural Pneumonectomy (EPP): Removes the affected lung, pleura, diaphragm, and part of the pericardium.
Pleurectomy/Decortication (P/D): Removes the pleura and visible tumors while sparing the lung.
Who It’s For: Patients with early-stage pleural or peritoneal mesothelioma.
Chemotherapy
What It Is: Chemotherapy uses drugs to kill cancer cells or slow their growth. The most common regimen combines cisplatin and pemetrexed (Alimta), which has been shown to extend survival times.
Who It’s For: Patients with advanced mesothelioma or those undergoing multimodal therapy (a combination of treatments).
Radiation Therapy
What It Is: Radiation therapy uses targeted energy beams to shrink tumors and relieve symptoms. It’s often used after surgery to destroy remaining cancer cells or as palliative care to reduce pain.
Who It’s For: Patients with localized mesothelioma or those needing symptom management.
Immunotherapy
What It Is: Immunotherapy helps the body’s immune system fight cancer. FDA-approved drugs like nivolumab (Opdivo) and ipilimumab (Yervoy) have shown promise in treating mesothelioma.
Who It’s For: Patients with advanced or recurrent mesothelioma, especially when other treatments have not worked.
Multimodal Therapy
What It Is: This approach combines two or more treatments—such as surgery, chemotherapy, and radiation therapy—to attack the disease from multiple angles.
Who It’s For: Patients with operable mesothelioma and good overall health.
Emerging Treatments and Clinical Trials
What It Is: Experimental treatments, including gene therapy, targeted therapies, and vaccine-based approaches, are being tested in clinical trials to improve outcomes for mesothelioma patients.
Who It’s For: Patients seeking cutting-edge therapies or those who have not responded to standard treatments.
Choosing the Right Treatment Plan
The best treatment plan depends on several factors, including the type and stage of mesothelioma, the histological subtype, and the patient’s overall health. A team of specialists—oncologists, surgeons, and radiologists—works together to create a personalized approach.
If you or a loved one has been diagnosed with mesothelioma, contact us today to explore your options. We can connect you with leading medical experts and help guide you through the legal process to secure compensation for treatment costs.
Securing Compensation for Mesothelioma Treatment Costs
Mesothelioma treatments, including surgery, chemotherapy, and immunotherapy, can be costly. For many patients and their families, the financial burden of medical care adds stress to an already challenging situation. However, individuals diagnosed with mesothelioma are often entitled to compensation that can help cover treatment costs, lost wages, and other expenses.
Asbestos Trust Claims
What They Are: Asbestos trust funds were established by companies that manufactured or used asbestos-containing products to compensate victims of asbestos exposure. With over $30 billion set aside in these trusts, they are a vital source of financial support for mesothelioma patients.
How It Helps: Trust claims are typically processed faster than lawsuits, providing funds to cover medical bills and related expenses without the need for court proceedings.
Learn more about asbestos trust claims.
Mesothelioma Lawsuits
What They Are: Filing a personal injury or wrongful death lawsuit allows victims or their families to seek compensation directly from companies responsible for asbestos exposure.
How It Helps: Successful lawsuits can result in significant settlements or verdicts, which can be used to fund cutting-edge treatments, experimental therapies, and ongoing care.
Learn more about mesothelioma lawsuits.
Disability Benefits
What They Are: Patients who are unable to work due to mesothelioma may qualify for Social Security Disability Insurance (SSDI) or veterans’ benefits if their exposure occurred during military service.
How It Helps: Disability benefits provide ongoing financial support for living expenses and treatment costs, offering crucial stability during this difficult time.
Learn more about asbestos disability claims.
Why Legal Action Matters
Pursuing legal compensation is about more than holding companies accountable—it’s about ensuring that mesothelioma patients have access to the best possible care. Funds secured through trust claims, lawsuits, or disability benefits can help cover:
Specialized treatments like surgery and immunotherapy.
Travel expenses for care at top mesothelioma treatment centers.
Clinical trial participation for experimental therapies.
Take the Next Step Toward Securing Compensation
If you or a loved one has been diagnosed with mesothelioma, our experienced legal team is here to help. We’ll guide you through the process of filing trust claims, pursuing lawsuits, or accessing disability benefits to alleviate the financial burden of treatment.
Call 833-4-ASBESTOS or fill out the contact form below for a free legal consultation.
Take the Next Step for Your Health and Your Family
If you or a loved one has been diagnosed with mesothelioma, it is almost certain that asbestos exposure is the cause. Many people exposed to asbestos were unknowingly put at risk by their employers or product manufacturers, and they may have unknowingly brought asbestos fibers home to their families. This means that not only are you entitled to compensation, but your loved ones may also be at risk of asbestos-related illnesses due to take-home exposure.
At our firm, we understand the devastating impact mesothelioma has on patients and their families. That’s why we provide comprehensive support to help you through this challenging time:
Free Health Tests for You and Your Family: If you have mesothelioma, we offer free health tests to your family members to ensure their well-being. Early detection can make a significant difference.
Free Legal Consultations: Our experienced legal team will guide you through the process of filing asbestos trust claims, pursuing lawsuits, or accessing disability benefits to secure the compensation you deserve.
Don’t wait—take control of your health and financial future today. Call us at 833-4-ASBESTOS or fill out the contact form below to schedule your free consultation and health tests.
Let us help you get the support you need to protect yourself and your loved ones.