Pleural Mesothelioma

Pleural mesothelioma is a rare and aggressive cancer that develops in the pleura, the thin membrane that lines the lungs and chest cavity. The pleura plays a vital role in the respiratory system by producing a lubricating fluid that allows the lungs to expand and contract smoothly during breathing.

This disease accounts for 75% to 90% of all mesothelioma cases, making it the most common form of the condition. Pleural mesothelioma is caused almost exclusively by exposure to asbestos fibers, which are inhaled and become lodged in the pleura. Over time, these fibers cause inflammation and scarring, which can lead to cellular mutations and cancer development.

The connection between asbestos and pleural mesothelioma was first identified in the mid-20th century, but cases continue to rise due to the disease’s long latency period, which can range from 20 to 50 years after exposure.

This page provides a comprehensive overview of pleural mesothelioma, including its causes, symptoms, diagnosis, and treatment options. If you or a loved one has been diagnosed, you may be entitled to legal compensation to cover medical costs and provide financial security for your family.

Mesothelioma is not a single, uniform disease. While it is classified by location in the body—such as pleural (lungs), peritoneal (abdomen), pericardial (heart), or testicular (testes)—it is also divided by cell type, known as histological subtypes. The three main subtypes are epithelioid, sarcomatoid, and biphasic, and each behaves differently and responds to treatment in unique ways. Learn more about histology and how it impacts mesothelioma treatment →

What Causes Pleural Mesothelioma?

The primary cause of pleural mesothelioma is exposure to asbestos, a naturally occurring mineral that was widely used in industrial, construction, and consumer products throughout the 20th century. When asbestos-containing materials are disturbed, they release tiny, sharp fibers into the air. These fibers are easily inhaled, becoming embedded in the pleura, the protective lining of the lungs.

Over time, these fibers cause chronic inflammation and scarring, which can damage cellular DNA and lead to cancer development. The disease’s long latency period, often between 20 and 50 years, means symptoms may not appear until decades after exposure.

Risk Factors for Pleural Mesothelioma

While asbestos exposure is the direct cause of pleural mesothelioma, certain factors increase the likelihood of developing the disease:

Occupational Exposure: Workers in industries that heavily used asbestos are at the highest risk. Jobs such as construction, shipbuilding, insulation installation, and automotive repair often involved handling or working near asbestos-containing products. These workers frequently inhaled airborne fibers during their daily tasks. [Learn more about occupations at risk →]

Asbestos Products: Many asbestos-containing products, including insulation, cement, brake pads, and gaskets, were responsible for exposing workers and consumers. The risk was particularly high when these products were cut, sanded, or otherwise disturbed. [Explore asbestos products →]

Industry-Specific Exposure: Certain industries, such as construction, maritime, and manufacturing, relied heavily on asbestos for its heat-resistant and durable properties. Workers in these industries were often exposed to large quantities of asbestos over extended periods. [Learn more about asbestos in industries →]

Secondary (Take-Home) Exposure: Family members of asbestos workers are also at risk. Asbestos fibers often clung to workers’ clothing, hair, or tools, unknowingly bringing the dangerous material home. Children and spouses were particularly vulnerable to this form of secondary exposure, which has caused many cases of pleural mesothelioma among family members. [Learn more about secondary exposure →]

Reducing Risk and Seeking Help
If you have been exposed to asbestos, whether through work, products, or a family member, it’s important to monitor your health closely. Early diagnosis can improve treatment outcomes, and legal compensation may be available to help cover medical costs and provide financial stability.

Symptoms of Pleural Mesothelioma

Pleural mesothelioma affects the pleura, the thin membrane around the lungs and chest cavity. As the disease progresses, tumors develop in this area, leading to a range of symptoms. These symptoms often stem from the tumors’ impact on lung function and fluid buildup in the chest cavity.

Recognizing these symptoms early is critical, as they are often mistaken for less serious respiratory issues.

Shortness of Breath (Dyspnea)

  • Why It Happens: Tumors in the pleura reduce the lungs’ ability to expand and contract, limiting airflow. Fluid buildup (pleural effusion) adds pressure, further restricting breathing.

  • What to Look For: A feeling of breathlessness, even during light activities, or difficulty catching your breath.

Persistent Chest Pain

  • Why It Happens: Tumors can irritate nerves in the chest wall or press on nearby tissues, causing sharp or aching pain. This pain is usually felt on the side of the chest where the cancer is growing.

  • What to Look For: Ongoing chest pain that doesn’t go away and may worsen with deep breaths or movement.

Pleural Effusion (Fluid Buildup)

  • Why It Happens: Tumors can cause inflammation and disrupt the pleura’s ability to drain fluid, leading to fluid accumulation between the lungs and chest wall.

  • Key Fact: Nearly all patients with pleural mesothelioma first experience pleural effusion, making it one of the earliest and most common symptoms.

  • What to Look For: A feeling of heaviness or tightness in the chest, along with difficulty breathing.

Chronic Dry Cough

  • Why It Happens: Tumor growth irritates the pleura and surrounding tissues, leading to a persistent, dry cough. Unlike a typical cough, this one doesn’t produce mucus and doesn’t go away over time.

  • What to Look For: A nagging cough that lingers and doesn’t respond to usual remedies.

Fatigue and Weakness

  • Why It Happens: Cancer increases inflammation and diverts nutrients to tumor growth, leaving the body with less energy. Reduced oxygen levels from impaired lung function also contribute to exhaustion.

  • What to Look For: Feeling unusually tired or weak, even after rest.

Unexplained Weight Loss

  • Why It Happens: Advanced cancers like mesothelioma speed up the body’s metabolism, causing it to burn more calories than usual. Symptoms like chest pain and fatigue can also reduce appetite, leading to weight loss.

  • What to Look For: Noticeable weight loss without trying, or a lack of appetite.

Fever and Night Sweats

  • Why It Happens: The body may react to tumor growth with systemic inflammation, causing mild fevers and excessive sweating, especially at night.

  • What to Look For: Frequent low-grade fevers or waking up drenched in sweat.

If you or a loved one are experiencing any of these symptoms, especially if there’s a history of asbestos exposure, it’s important to consult a doctor as soon as possible. Early diagnosis can make a significant difference in treatment options and outcomes.

When to Seek Medical Attention
If you experience any of these symptoms and have a history of asbestos exposure, it’s critical to consult a medical professional as soon as possible. Pleural mesothelioma symptoms often resemble those of more common conditions, such as pneumonia or chronic obstructive pulmonary disease (COPD), leading to delays in diagnosis.

Take the Next Step
Our firm offers free asbestos health tests for individuals experiencing mesothelioma symptoms or who have been exposed to asbestos. Early detection can make a significant difference in treatment options and outcomes. Contact us today to schedule a free evaluation.

Diagnosing Pleural Mesothelioma

Why Early Diagnosis is Crucial
Diagnosing pleural mesothelioma can be tricky because its symptoms often look like those of more common lung conditions, such as pneumonia or chronic obstructive pulmonary disease (COPD). However, getting an accurate diagnosis as early as possible is critical. It allows doctors to create a treatment plan tailored to your needs and can improve your overall outlook.

How Pleural Mesothelioma is Diagnosed
1. Medical History and Physical Exam
The first step in diagnosing pleural mesothelioma is a thorough review of your medical history. Doctors will ask about any past exposure to asbestos, which is the leading cause of this disease.

During the physical exam, they’ll check for signs like fluid buildup in your chest or reduced lung function. If anything unusual is found, they’ll recommend further testing.

2. Imaging Tests
Imaging studies are essential for spotting abnormalities in the chest cavity and understanding how far the disease has progressed. Here are the most common imaging tools used:

Chest X-Ray: This is often the first test doctors use. It can show pleural thickening or fluid buildup (pleural effusion).
CT Scan: A CT scan provides detailed, cross-sectional images of your chest, helping to locate tumors and assess fluid buildup.
MRI: This test gives a closer look at soft tissues, making it easier to see if the cancer has spread to nearby areas.
PET Scan: A PET scan highlights active cancer cells and helps determine the stage of the disease.
3. Biopsy: The Gold Standard for Diagnosis
While imaging tests can suggest mesothelioma, a biopsy is the only way to confirm it. During a biopsy, doctors collect a small sample of tissue to examine under a microscope. This helps confirm the presence of cancer and identify its specific type.

Here are the most common biopsy methods:

Thoracoscopy: A minimally invasive procedure where a small camera and tools are inserted into the chest to collect tissue samples.
Needle Biopsy: A less invasive option that uses a needle to extract fluid or tissue for testing.
4. Staging the Disease
Once mesothelioma is confirmed, doctors use staging to determine how far the cancer has spread. This step is crucial for deciding on the best treatment approach.

What is Staging?
Staging looks at whether the cancer is confined to the chest cavity or has spread to other parts of the body.

Why It Matters:

Early Stages (1 and 2): The cancer is localized, and aggressive treatments like surgery may still be an option.
Advanced Stages (3 and 4): The cancer has spread, so treatment focuses on managing symptoms and improving quality of life.
For more details on mesothelioma staging and how it affects treatment options, visit our dedicated page: [Learn more about mesothelioma staging →].

Final Thoughts
Diagnosing pleural mesothelioma is a multi-step process that requires careful evaluation. If you or a loved one have symptoms and a history of asbestos exposure, don’t wait—talk to your doctor about getting tested. Early diagnosis can make all the difference.

When to Seek Testing
If you have a history of asbestos exposure and are experiencing symptoms like chest pain, shortness of breath, or persistent coughing, it’s crucial to seek medical attention immediately. Early diagnosis can open the door to more treatment options and improve outcomes.

Free Asbestos Health Tests
Our firm offers free asbestos health tests for individuals and their families. These tests can help identify early signs of asbestos-related diseases and provide peace of mind for those at risk. Contact us today to schedule a free evaluation.

Treatment Options for Pleural Mesothelioma


Overview of Treatment Options
When it comes to treating pleural mesothelioma, the main goals are to remove or shrink tumors, manage symptoms, and improve quality of life. The right treatment plan depends on several factors, including the stage of the disease, your overall health, and the specific characteristics of your cancer.

Most patients receive a combination of therapies, called multimodal treatment. This approach may include surgery, chemotherapy, radiation, and newer options like immunotherapy. Let’s take a closer look at the most common treatment options available.

1. Surgery
What’s the Goal?
Surgery is often used to remove as much of the cancer as possible, especially in the early stages of mesothelioma.

Types of Surgery:
Extrapleural Pneumonectomy (EPP):
This is a more aggressive surgery that removes the affected lung, the pleura (lining of the lung), part of the diaphragm, and the pericardium (lining around the heart). It’s typically done in early-stage cases to try to remove all visible cancer.
Pleurectomy/Decortication (P/D):
This is a less invasive option that removes the pleura and visible tumors but spares the lung. It’s often used to relieve symptoms or as part of a larger treatment plan.
[Learn more about surgery for pleural mesothelioma →]

2. Chemotherapy
What’s the Goal?
Chemotherapy uses powerful drugs to kill cancer cells or slow their growth. It can be used on its own or alongside surgery to improve outcomes.

Most Common Chemotherapy Regimen:
The combination of pemetrexed (Alimta) and cisplatin is considered the gold standard for mesothelioma treatment. This combination has been shown to shrink tumors and extend survival for many patients.

[Learn more about chemotherapy for pleural mesothelioma →]

3. Radiation Therapy
What’s the Goal?
Radiation therapy uses high-energy beams to target and destroy cancer cells. It’s often used to:

Kill any remaining cancer cells after surgery.
Relieve symptoms like pain or breathing difficulties in advanced cases.
[Learn more about radiation therapy for pleural mesothelioma →]

4. Immunotherapy
What’s the Goal?
Immunotherapy helps your body’s immune system recognize and attack cancer cells.

FDA-Approved Options:
Nivolumab (Opdivo) and Ipilimumab (Yervoy):
This combination immunotherapy has been approved for pleural mesothelioma and has shown promise in extending survival for some patients.
[Learn more about immunotherapy for pleural mesothelioma →]

5. Emerging Treatments and Clinical Trials
What’s the Goal?
Researchers are constantly working on new treatments to improve outcomes for mesothelioma patients. These include:

Gene Therapy: Altering genes to fight cancer.
Targeted Therapies: Drugs that target specific cancer cells while sparing healthy ones.
Mesothelioma Vaccines: Experimental treatments designed to boost the immune system.
Why Consider Clinical Trials?
Access to cutting-edge treatments that aren’t widely available yet.
An opportunity to contribute to advancements in mesothelioma research.
[Learn more about mesothelioma clinical trials →]

6. Palliative Care
What’s the Goal?
Palliative care focuses on relieving symptoms and improving quality of life, especially for patients with advanced mesothelioma.

Common Approaches:
Managing Pain: Using medications or nerve blocks.
Draining Fluid Buildup: Procedures like thoracentesis or pleurodesis can help reduce discomfort.
Improving Breathing: Supplemental oxygen or pulmonary rehabilitation can make breathing easier.
Developing a Personalized Treatment Plan
No two cases of pleural mesothelioma are the same, which is why treatment plans are tailored to each patient. A team of specialists—including oncologists, thoracic surgeons, and radiologists—will work together to create a plan that’s right for you. Their goal is to maximize the effectiveness of treatment while minimizing side effects.

Final Thoughts
If you or a loved one has been diagnosed with pleural mesothelioma, it’s important to know that there are many treatment options available. From surgery to emerging therapies, your care team will guide you through the process and help you make informed decisions about your treatment.

If you or a loved one has been diagnosed with pleural mesothelioma, it’s important to explore your options early. Contact us to learn more about available treatments and how to access financial support to cover medical costs.

Call 833-4-ASBESTOS or fill out the form below to schedule a free consultation.

Prognosis and Survival Rates for Pleural Mesothelioma
Understanding the Prognosis for Pleural Mesothelioma
A diagnosis of pleural mesothelioma can feel overwhelming, but it’s important to know that survival rates and outcomes vary widely depending on individual factors. These include the stage of the disease at diagnosis, the patient’s overall health, and the treatments pursued. While mesothelioma is often associated with poor long-term survival, advancements in medical care are offering hope and improving outcomes for many patients.

One key aspect of mesothelioma is its long latency period—often 20 to 60 years after asbestos exposure. This means it’s typically diagnosed in older adults, often in their 70s or beyond. While the 5-year survival rate for mesothelioma remains low, it’s worth noting that for many older patients, a 5-year horizon may align with their general life expectancy. As a result, the focus often shifts to maintaining quality of life and ensuring access to the best possible care.

Factors That Affect Prognosis
1. Stage at Diagnosis

Early-Stage (Stages 1 and 2): When tumors are localized, patients may qualify for surgery and multimodal treatments, which can significantly improve survival times.
Advanced-Stage (Stages 3 and 4): At this stage, the cancer is more widespread, and treatment typically focuses on managing symptoms and improving comfort.
For more on staging and its impact on treatment, see this guide on mesothelioma staging.

2. Histological Subtype

Epithelioid Mesothelioma: This subtype responds better to treatment and offers the best survival rates.
Sarcomatoid and Biphasic Mesothelioma: These subtypes are more aggressive and harder to treat.
Learn more about mesothelioma subtypes and their differences here.

3. Patient’s Age and Overall Health

Mesothelioma is most commonly diagnosed in older adults. However, patients in good general health often tolerate treatments better, which can improve outcomes.
4. Treatment Plan

A multimodal approach—combining surgery, chemotherapy, and radiation—can extend survival for eligible patients.
Access to clinical trials and emerging therapies offers hope, especially for advanced cases.
Explore current treatment options and clinical trials here.

Survival Rates for Pleural Mesothelioma
Survival statistics provide a general picture but don’t define individual outcomes. Recent data suggest the following:

1-Year Survival Rate: About 40% to 50% of patients survive at least one year after diagnosis.
3-Year Survival Rate: Around 10% to 20% survive three years, with better outcomes for those diagnosed early or with epithelioid mesothelioma.
5-Year Survival Rate: Less than 10% survive five years, though these numbers are improving with advances in treatment.
For older patients diagnosed in their 70s or 80s, survival rates may seem discouraging when viewed alone. However, many older individuals focus on managing symptoms and maintaining quality of life, aligning treatment goals with their overall life expectancy.

Improving Survival and Quality of Life
Early Diagnosis: Detecting mesothelioma early opens the door to more treatment options.
Specialized Care: Receiving treatment from experienced mesothelioma specialists can make a significant difference in outcomes.
Palliative Care: Managing symptoms like pain, shortness of breath, and fatigue can greatly enhance quality of life, even in advanced stages.
For tips on finding specialized care, visit this resource.

Hope Through Advancements in Treatment
Ongoing research into immunotherapy, gene therapy, and targeted therapies is extending survival times and providing new options for mesothelioma patients. Clinical trials offer access to cutting-edge treatments and are a source of hope for patients and families navigating this diagnosis.

Stay updated on the latest advancements in mesothelioma treatment here.

Take the Next Step
If you or a loved one has been diagnosed with pleural mesothelioma, it’s important to know your options. Our team is here to connect you with leading medical specialists and help you secure financial compensation to cover the cost of treatment and care.

Call 833-4-ASBESTOS or fill out the form below for a free consultation.

Living with Pleural Mesothelioma
Adapting to Life with Pleural Mesothelioma
A diagnosis of pleural mesothelioma brings significant changes, not just for the person with the disease but also for their caregivers and loved ones. While the journey may be challenging, there are many resources and strategies available to help manage symptoms, maintain quality of life, and navigate day-to-day living.

Coping with Physical Symptoms
Managing the physical symptoms of pleural mesothelioma is key to improving comfort and maintaining independence. Strategies include:

Symptom Management: Palliative care can alleviate pain, ease breathing difficulties, and reduce fatigue. Techniques like thoracentesis to remove pleural effusions or medications to manage pain can significantly improve quality of life.
Maintaining Nutrition: Appetite loss and weight loss are common, but working with a nutritionist can help ensure proper nutrition to maintain energy and strength.
Staying Active: Gentle activities, like walking or stretching, can improve lung capacity, reduce fatigue, and boost mood.
Emotional and Psychological Well-Being
The emotional toll of mesothelioma can be as significant as the physical challenges. It’s crucial to address mental health and emotional needs:

Support Groups: Connecting with others who are facing similar challenges can reduce feelings of isolation. Many mesothelioma-specific support groups are available online and in-person.
Counseling and Therapy: Talking to a counselor or therapist can help process the emotional impact of the diagnosis and develop coping strategies.
Mindfulness and Relaxation Techniques: Practices like meditation, yoga, or guided breathing can help reduce anxiety and improve focus.
Caregiver Support
Caregivers often play a vital role in helping mesothelioma patients manage their daily lives, but caregiving can be physically and emotionally demanding. Resources and tips for caregivers include:

Respite Care: Temporary relief care can give caregivers time to recharge while ensuring their loved one is well cared for.
Education: Learning about mesothelioma and its treatment options helps caregivers make informed decisions and provide better support.
Support Networks: Caregiver support groups offer a space to share experiences, seek advice, and connect with others in similar situations.
Financial Stability and Legal Settlements
Mesothelioma care often comes with significant costs, including medical bills, travel expenses, and lost income. Legal settlements and asbestos trust claims can provide crucial financial support to alleviate these burdens. Many of our clients have found that compensation not only helps cover treatment costs but also allows them to focus on their health and spend more quality time with loved ones.

In addition to financial relief, settlements often provide peace of mind, ensuring that patients and their families have the resources they need for care, support, and maintaining quality of life.

Take Steps Toward a Better Tomorrow
Living with pleural mesothelioma requires a comprehensive approach that addresses physical, emotional, and financial well-being. Whether you’re a patient or a caregiver, remember that support is available, and you don’t have to face this journey alone.

If you need guidance on navigating mesothelioma treatment, managing symptoms, or exploring financial support through legal settlements, we’re here to help. Contact us today for compassionate and experienced support.

Call 833-4-ASBESTOS or fill out the form below for a free consultation.

Legal Options for Pleural Mesothelioma Patients
Securing Financial Support Through Legal Action
Pleural mesothelioma is almost always linked to asbestos exposure, meaning that most patients are eligible for financial compensation. Legal settlements, asbestos trust claims, and disability benefits can provide crucial financial relief, helping to cover medical bills, lost wages, and other expenses. For many patients, this compensation plays a critical role in improving their quality of life and reducing the financial burden on their families.

1. Asbestos Trust Claims
What Are They?
Asbestos trust funds were established by companies that used or manufactured asbestos products to compensate individuals who develop asbestos-related diseases.

Why They’re Important for Mesothelioma Patients:

Priority Payments: Patients with mesothelioma often receive higher payouts than those with less severe asbestos-related conditions.
Speed of Payment: In many cases, we can secure initial trust payments for mesothelioma patients within 30 days, providing immediate financial relief.
[Learn more about asbestos trust claims →]

2. Mesothelioma Lawsuits
What Are They?
Personal injury lawsuits allow mesothelioma patients to seek compensation directly from companies responsible for their asbestos exposure.

Benefits of Filing a Lawsuit:

Substantial settlements or verdicts to cover treatment costs and provide financial security.
Opportunity to hold negligent companies accountable for their role in exposing workers to asbestos.
[Learn more about mesothelioma lawsuits →]

3. Disability Benefits
Social Security Disability Insurance (SSDI):
Mesothelioma qualifies as a compassionate allowance condition under SSDI, meaning applications are fast-tracked for approval.

Veterans’ Benefits:
Many veterans were exposed to asbestos during their military service, particularly in shipbuilding, aviation, and other high-risk roles. Veterans diagnosed with mesothelioma may be eligible for disability benefits through the Department of Veterans Affairs (VA).

[Learn more about asbestos disability claims →]

4. Why Legal Action Matters
Compensation from trust funds, lawsuits, or disability benefits can help cover:

Cutting-edge treatments, including clinical trials and experimental therapies.
Travel and lodging expenses for treatment at specialized mesothelioma centers.
Everyday expenses, ensuring financial stability for patients and their families.
Beyond financial relief, pursuing legal action can provide a sense of justice and accountability, knowing that negligent companies are being held responsible for their actions.

Take Action Today to Secure Compensation
If you or a loved one has been diagnosed with pleural mesothelioma, don’t wait to explore your legal options. Our experienced team can help you navigate asbestos trust claims, file lawsuits, and secure disability benefits, ensuring you get the compensation you deserve.

Seek the Compensation You Deserve
A diagnosis of pleural mesothelioma is life-changing, not only for the patient but also for their loved ones. If you or a family member is facing this disease, it’s important to remember that seeking compensation isn’t about greed—it’s about justice and security. The companies responsible for exposing workers and their families to asbestos knew the risks but failed to protect those in harm’s way.

By pursuing compensation, you’re not just holding those companies accountable—you’re securing the resources you and your family need for medical care, everyday expenses, and peace of mind. Financial relief can also ease the burden on your loved ones, allowing you to focus on what matters most: spending time together and maintaining the best possible quality of life.

Our experienced team has helped thousands of mesothelioma patients and their families access asbestos trust payments, file lawsuits, and secure disability benefits. Many of our clients have received initial payments in as little as 30 days, providing immediate financial support when it’s needed most.

We’re Here to Help—Every Step of the Way
Whether you need guidance on treatment options, financial assistance, or legal representation, we’re here to stand by your side.

Contact us today for a free consultation:

Call: 833-4-ASBESTOS
Fill Out the Form Below: Our team will reach out to you promptly to discuss your options.
You’ve faced enough challenges—let us take on the fight for justice and compensation so you can focus on your health and your family.

Call 833-4-ASBESTOS or fill out the form below for a free consultation.