Cisplatin

Term: CisplatinDefinition: Cisplatin is a chemotherapy drug used in the treatment of various cancers, including mesothelioma, which can be caused by asbestos exposure.Phonetic Pronunciation: (sis-PLAH-tin)Origin: The name "cisplatin" is derived from its chemical structure, which includes a platinum atom. The prefix "cis" refers to the arrangement of the ligands around the platinum atom in the molecule, a term derived from Latin meaning "on this side." The use of platinum in medicine can be traced back to ancient times, but cisplatin was first synthesized in the 19th century and later discovered to have anticancer properties in the 1960s.Significance in Asbestos Context: Cisplatin is significant in the context of asbestos-related diseases because it is commonly used in the treatment of mesothelioma, a cancer strongly linked to asbestos exposure. Its use can improve survival rates and quality of life for patients diagnosed with this aggressive cancer, making it a critical component of treatment plans for those affected by asbestos.Example Sentence: After being diagnosed with mesothelioma due to asbestos exposure, the patient began a treatment regimen that included the chemotherapy drug cisplatin.Related Terms: Chemotherapy, Mesothelioma, Asbestos Exposure, Cancer Treatment, Palliative CareNotes: - Cisplatin is often used in combination with other drugs to enhance its effectiveness. - It can have significant side effects, including kidney damage and hearing loss, which must be managed carefully. - While effective, cisplatin is not a cure for mesothelioma but can extend life and improve symptoms.