Extra Cellular Matrix

Term: Extra Cellular MatrixDefinition: The extracellular matrix (ECM) is a complex network of proteins and carbohydrates that provides structural and biochemical support to surrounding cells.Phonetic Pronunciation: (ek-struh-SEL-yuh-lur MA-trix)Origin: The term "extracellular" comes from the Latin words "extra," meaning outside, and "cellular," from "cellula," meaning a small room or cell. "Matrix" is derived from the Latin "mater," meaning mother, and refers to something that gives form, shape, or structure.Significance in Asbestos Context: In the context of asbestos exposure, the extracellular matrix is significant because asbestos fibers can disrupt the normal function of the ECM, leading to inflammation and fibrosis. This disruption is a key factor in the development of asbestos-related diseases such as mesothelioma and asbestosis.Example Sentence: "Research has shown that asbestos fibers can cause significant alterations to the extracellular matrix, contributing to the progression of asbestos-related lung diseases."Related Terms: Fibrosis, Mesothelioma, Asbestosis, Inflammation, CollagenNotes: - The ECM is not only affected by asbestos but also plays a role in the body's response to the fibers. - Alterations in the ECM can lead to both the onset and progression of asbestos-related diseases.