FOLFIRI (5-FU, Leucovorin, and Irinotecan)

Term: FOLFIRI (5-FU, Leucovorin, and Irinotecan)Definition: FOLFIRI is a chemotherapy regimen used in the treatment of advanced colorectal cancer, consisting of the drugs 5-Fluorouracil (5-FU), Leucovorin, and Irinotecan.Phonetic Pronunciation: (FOL-fih-ree)Origin: The term FOLFIRI is derived from the names of its constituent drugs: Folinic acid (another name for Leucovorin), Fluorouracil (5-FU), and Irinotecan. The acronym simplifies the identification of this specific combination therapy.Significance in Asbestos Context: While FOLFIRI is not directly used for treating asbestos-related diseases, it is relevant in the broader context of cancer treatments. Some individuals exposed to asbestos may develop colorectal cancer as a secondary malignancy, making FOLFIRI a potential treatment option in those cases.Example Sentence: After being diagnosed with colorectal cancer linked to his asbestos exposure, the patient was prescribed FOLFIRI to manage the progression of his disease.Related Terms: Chemotherapy, Colorectal Cancer, 5-Fluorouracil, Leucovorin, IrinotecanNotes: - FOLFIRI is typically administered in cycles, often in combination with other treatments. - It is not a standard treatment for mesothelioma or other primary asbestos-related cancers.