Hyaluronic Acid

Term: Hyaluronic AcidDefinition: A high-molecular-weight glycosaminoglycan that is a major component of the extracellular matrix and plays a role in tissue hydration and lubrication.Phonetic Pronunciation: (hye-luh-RAHN-ik AS-id)Origin: The term "hyaluronic" is derived from the Greek word "hyalos," meaning glass, due to its clear appearance in solution. The term "acid" refers to its chemical nature. It was first isolated from the vitreous humor of the eye in 1934 by Karl Meyer and John Palmer.Significance in Asbestos Context: Hyaluronic acid levels in pleural fluid can be elevated in cases of asbestos-related diseases such as mesothelioma. Monitoring these levels can aid in the diagnosis and management of asbestos-related conditions, providing insights into the severity and progression of the disease.Example Sentence: Elevated levels of hyaluronic acid in the pleural fluid were detected in the patient, indicating possible asbestos exposure and the development of mesothelioma.Related Terms: Mesothelioma, Pleural Effusion, Extracellular Matrix, Glycosaminoglycan, AsbestosisNotes: - Hyaluronic acid is not specific to asbestos-related diseases and can be elevated in other conditions as well. - It is used in various medical applications, including joint lubrication and wound healing.