OX40 receptor

Term: OX40 receptorDefinition: A protein receptor found on the surface of activated T-cells, which plays a crucial role in the immune system's response to infection and disease, including asbestos-related conditions.Phonetic Pronunciation: (oh-ex-forty ree-SEP-tor)Origin: The term "OX40" originates from the Oxford University where it was first identified. The "OX" refers to Oxford, and "40" indicates it was the 40th monoclonal antibody developed in a series. The term "receptor" comes from the Latin word "receptus," meaning "received," reflecting the receptor's role in receiving signals.Significance in Asbestos Context: The OX40 receptor is significant in asbestos-related diseases because it is involved in the activation and proliferation of T-cells, which can be crucial in the immune response to asbestos-induced inflammation and potential tumor development. Understanding the role of OX40 can aid in developing targeted therapies for asbestos-related conditions.Example Sentence: Recent research has shown that targeting the OX40 receptor could potentially enhance the immune response in patients suffering from asbestos-related lung diseases.Related Terms: T-cell, immune response, inflammation, monoclonal antibody, targeted therapyNotes: - The OX40 receptor is not exclusive to asbestos-related diseases but is part of broader immune system research. - Therapies targeting the OX40 receptor are still in experimental stages and not yet standard treatments for asbestos-related diseases.