Definition:
The OX40 receptor is a protein found on the surface of T-cells, a type of immune cell. It plays a critical role in regulating the immune response by promoting T-cell activation, survival, and proliferation.
Phonetic Pronunciation:
(oks-FOUR-tee ree-SEP-tor)
Etymological Origin:
The term "OX40" originates from its discovery in a specific subset of T-cells during research on immune system markers. "OX" refers to the Oxford designation system used in immunology, and "40" is the numerical identifier assigned to this receptor. "Receptor" comes from the Latin recipere, meaning "to receive," indicating its role in receiving signals.
Significance in Asbestos Context:
The OX40 receptor is significant in the context of asbestos-related diseases because it is being studied as a potential target for immunotherapy in cancers like mesothelioma. Asbestos exposure can lead to mesothelioma, a cancer that often evades the immune system. Therapies targeting the OX40 receptor aim to enhance the immune system's ability to recognize and attack cancer cells, offering a promising avenue for treatment.
Synonyms or Related Terms:
Example Sentence:
"Emerging immunotherapies targeting the OX40 receptor show potential in boosting the immune response against mesothelioma caused by asbestos exposure."
Common Misconceptions:
