Pemetrexed

Term: PemetrexedDefinition: Pemetrexed is a chemotherapy drug used to treat mesothelioma, a cancer often linked to asbestos exposure, by inhibiting the growth of cancer cells.Phonetic Pronunciation: (peh-meh-TREX-ed)Origin: The term "Pemetrexed" is derived from its chemical structure and classification as an antifolate. The "pem" prefix refers to its chemical moiety, while "etrexed" indicates its relation to other drugs in the same class, such as methotrexate. The name reflects modern pharmaceutical naming conventions, which often combine elements of the drug's structure and function.Significance in Asbestos Context: Pemetrexed is significant in the context of asbestos-related diseases because it is a primary treatment for malignant pleural mesothelioma, a cancer strongly associated with asbestos exposure. Its use can improve patient outcomes and quality of life, making it a critical component in the medical management of asbestos-related cancers.Example Sentence: "After his diagnosis of mesothelioma due to asbestos exposure, John started a treatment regimen that included the chemotherapy drug Pemetrexed."Related Terms: Chemotherapy, Mesothelioma, Antifolate, Alimta, Asbestos-related cancerNotes: - Pemetrexed is often marketed under the brand name Alimta. - It is typically used in combination with other drugs, such as cisplatin, for better efficacy. - Patients receiving Pemetrexed may need to take folic acid and vitamin B12 supplements to reduce side effects.