Pemetrexed

Type: Medical Term

Term: Pemetrexed

Definition: Pemetrexed is a chemotherapy drug that works by interfering with the ability of cancer cells to replicate and grow, specifically targeting enzymes involved in DNA and RNA synthesis.

Phonetic Pronunciation: (peh-meh-TREK-sed)

Etymological Origin: The name "Pemetrexed" is derived from its chemical structure and function. "Peme-" may relate to its chemical composition, while "-trexed" is a suffix commonly used in naming chemotherapy drugs, indicating its role as an antineoplastic (anti-cancer) agent.

Significance in Asbestos Context: Pemetrexed is highly significant in the field of asbestos because it is one of the primary drugs used in the treatment of malignant pleural mesothelioma, a cancer strongly linked to asbestos exposure. It is often used in combination with cisplatin to improve survival rates and manage symptoms in patients diagnosed with this aggressive cancer. Its role in treatment makes it a critical component of medical care for individuals affected by asbestos-related diseases.

Synonyms or Related Terms: Alimta (brand name), antifolate chemotherapy, cisplatin combination therapy.

Example Sentence: "Pemetrexed, in combination with cisplatin, is the standard first-line treatment for patients diagnosed with malignant pleural mesothelioma caused by asbestos exposure."

Common Misconceptions:

  1. Misconception: Pemetrexed cures mesothelioma.
    Clarification: Pemetrexed does not cure mesothelioma but helps to slow the progression of the disease and improve quality of life.
  2. Misconception: Pemetrexed is effective for all cancers.
    Clarification: Pemetrexed is specifically approved for use in mesothelioma and certain types of lung cancer; it is not universally effective for all cancers.
  3. Misconception: Pemetrexed can be used without other treatments.
    Clarification: Pemetrexed is often used in combination with other drugs, such as cisplatin, to enhance its effectiveness in treating mesothelioma.