Phagocytosis

Term: PhagocytosisDefinition: The process by which cells engulf and digest solid particles, such as asbestos fibers, to remove them from the body.Phonetic Pronunciation: (fag-uh-SY-toh-sis)Origin: The term 'phagocytosis' originates from the Greek words 'phagein,' meaning 'to eat,' and 'kytos,' meaning 'cell.' It was coined in the late 19th century by Élie Metchnikoff, who discovered this cellular process.Significance in Asbestos Context: Phagocytosis is crucial in understanding how the body attempts to clear asbestos fibers. When asbestos fibers are inhaled, macrophages in the lungs try to engulf and break down these fibers. However, asbestos can be resistant to this process, leading to chronic inflammation and potential disease development.Example Sentence: The inability of macrophages to fully clear asbestos fibers through phagocytosis can contribute to the development of asbestos-related diseases.Related Terms: Macrophage, Asbestosis, Inflammation, Clearance Mechanism, Cellular ResponseNotes: - Phagocytosis is not always effective against asbestos due to the durability of the fibers. - Chronic exposure can overwhelm the body's phagocytic capacity. - Research continues to explore ways to enhance phagocytic activity to mitigate asbestos-related health risks.