Definition:
Tumorigenesis refers to the process by which normal cells transform into cancerous cells, leading to the formation and development of tumors.
Phonetic Pronunciation:
(too-mor-ih-JEN-eh-sis)
Etymological Origin:
The term "tumorigenesis" is derived from the Latin word "tumor," meaning "swelling" or "mass," and the Greek suffix "-genesis," meaning "origin" or "creation." Together, it signifies the origin or creation of tumors.
Significance in Asbestos Context:
Tumorigenesis is a critical concept in the field of asbestos because asbestos exposure is a well-documented cause of tumorigenesis, particularly in the lungs and mesothelium. Asbestos fibers can induce genetic and cellular damage, leading to the initiation and promotion of cancerous growths such as mesothelioma and lung cancer. Understanding tumorigenesis helps researchers and medical professionals identify how asbestos contributes to cancer development and informs both treatment strategies and litigation related to asbestos exposure.
Synonyms or Related Terms:
Example Sentence:
"The tumorigenesis of mesothelioma is strongly linked to prolonged asbestos exposure, as the fibers cause cellular damage and genetic mutations over time."
Common Misconceptions: