VEGF inhibitors

Term: VEGF inhibitorsDefinition: VEGF inhibitors are drugs that block the vascular endothelial growth factor, reducing the formation of new blood vessels that can feed tumor growth. They are used in the treatment of certain cancers, including those related to asbestos exposure.Phonetic Pronunciation: (VEE-gef in-HIB-it-ers)Origin: The term "VEGF" stands for Vascular Endothelial Growth Factor, derived from the scientific nomenclature describing its function in the body. "Inhibitors" comes from the Latin "inhibere," meaning to hold back or restrain, indicating the drug's action on the VEGF pathway.Significance in Asbestos Context: In the context of asbestos-related diseases, particularly mesothelioma, VEGF inhibitors are significant because they target the angiogenesis that supports tumor growth. By inhibiting this process, these drugs can potentially slow down the progression of the cancer, offering a therapeutic option for patients affected by asbestos exposure.Example Sentence: "The oncologist recommended starting treatment with VEGF inhibitors to manage the patient's asbestos-related mesothelioma."Related Terms: angiogenesis, mesothelioma, targeted therapy, cancer treatment, anti-angiogenic agentsNotes: - VEGF inhibitors are part of a broader class of drugs known as anti-angiogenic agents. - These drugs are often used in combination with other cancer treatments. - Not all patients with asbestos-related diseases will be candidates for VEGF inhibitors, as treatment decisions are individualized.