Experimental infective Pneumoconiosis Effect of asbestos dust on Rhesus Monkeys - (1973)

Authors: S.H. Zaidi,R. Shanker,R.K.S. Dogha
Published In: Environmental Research

The Combined Effects of Asbestos Dust and Candida albicans on Lung Health: A Study Overview

Abstract The study titled "Experimental Infective Pneumoconiosis: Effect of Asbestos Dust and Candida albicans Infection on the Lungs" was published in Environmental Research in 1973. Conducted by the Industrial Toxicology Research Centre in Lucknow, India, the research explored the combined effects of amosite asbestos dust and Candida albicans infection on the lungs of rhesus monkeys. Over a 330-day period, the study revealed that the combination of these factors caused extensive coalescent fibrosis in the lungs, a condition far more severe than the effects of either factor alone. The findings highlight the potential for synergistic damage when asbestos exposure is combined with infections, providing critical insights into the progression of asbestos-related diseases.


Legal Relevance This study provides compelling evidence for individuals pursuing asbestos-related legal claims. The findings demonstrate that exposure to asbestos dust, particularly amosite, can lead to severe lung damage, including fibrosis. The study also underscores the role of secondary factors, such as infections, in exacerbating asbestos-related conditions. This is particularly relevant in legal cases where defendants argue that other health conditions, such as infections, are the primary cause of lung damage rather than asbestos exposure.

Key legal takeaways include:

  • Evidence Pathways: The study establishes a clear link between asbestos exposure and progressive lung fibrosis, supporting claims of occupational exposure leading to severe health outcomes.
  • Occupational History Relevance: The findings reinforce the importance of documenting workplace exposure to asbestos, especially in industries where amosite asbestos was prevalent.
  • Counterarguments to Defense Claims: The study refutes common defense arguments that infections alone are responsible for lung damage, showing that asbestos exposure significantly worsens the impact of infections.

For individuals seeking compensation for asbestos-related diseases, this study strengthens the argument that asbestos exposure is a primary and aggravating factor in lung damage.


Occupation Groups at Risk The study's findings are particularly relevant to individuals in occupations with high asbestos exposure. These include:

  1. Construction Workers: Frequently exposed to asbestos-containing materials such as insulation, cement, and roofing products, construction workers are at high risk of inhaling asbestos fibers.
  2. Shipyard Workers: Asbestos was widely used in shipbuilding for insulation and fireproofing, putting shipyard workers at significant risk.
  3. Industrial Workers: Those in manufacturing industries, particularly those handling asbestos-containing products like textiles, gaskets, and brake linings, face elevated exposure risks.
  4. Miners: Workers in asbestos mines or those mining other minerals contaminated with asbestos are directly exposed to raw asbestos fibers.
  5. Firefighters: Often exposed to asbestos during building fires or demolitions, firefighters face risks from disturbed asbestos-containing materials.
  6. Power Plant Workers: Asbestos was commonly used in power plants for insulation, exposing workers to fibers during maintenance or repairs.
  7. Demolition Workers: The destruction of older buildings containing asbestos materials releases fibers into the air, endangering demolition crews.

These occupations are at heightened risk due to the frequent and prolonged exposure to asbestos fibers, which can lead to severe health conditions such as asbestosis, mesothelioma, and lung cancer.


Current Medical Understanding The study aligns with current medical knowledge regarding the health risks of asbestos exposure. It confirms that asbestos fibers, particularly amosite, can cause severe lung damage, including fibrosis and other chronic conditions. While the specific interaction between asbestos and Candida albicans is less emphasized in modern literature, the study's findings on the exacerbation of lung damage by infections remain relevant. Contemporary research continues to explore how secondary factors, such as infections or co-exposures, may worsen asbestos-related diseases.


Citation Industrial Toxicology Research Centre. (1973). Experimental Infective Pneumoconiosis: Effect of Asbestos Dust and Candida albicans Infection on the Lungs. Environmental Research, 6(2), 271-286.


National Library of Medicine Link Unfortunately, a direct link to the National Library of Medicine's page for this specific study is not available. However, readers can explore related studies on asbestos exposure and its health effects at PubMed.


Contact Us Today If you or a loved one has been diagnosed with an asbestos-related disease such as mesothelioma, lung cancer, stomach cancer, throat cancer, colon cancer, asbestosis, or pleural plaques, you may be entitled to compensation. Our experienced legal team specializes in asbestos-related claims and can help you navigate the legal process to secure the justice and financial support you deserve.

Contact us today for a free consultation. Let us help you hold those responsible for your asbestos exposure accountable and ensure you receive the compensation you need to cover medical expenses, lost wages, and more.