Women and Mesothelioma - (2002)

Authors: Dorsett D. Smith MD
Published In: Chest

Women and Mesothelioma: Legal Implications of Environmental Asbestos Exposure

Abstract
The study "Women and Mesothelioma," published in CHEST (2002) by Metintas et al., investigates the relative risk of malignant pleural mesothelioma (MPM) in women compared to men due to environmental exposure to amphibole asbestos. The research, conducted in Turkey, found that women had a significantly higher relative risk of MPM (159.8 per 100,000) compared to men (114.8 per 100,000). The study also highlights the role of environmental exposure to erionite, a highly carcinogenic fibrous zeolite, and discusses the relationship between asbestos dose, latency periods, and the pathology of mesothelioma. These findings provide critical insights into the risks faced by women exposed to asbestos in non-occupational settings.

Legal Relevance
This study is a vital resource for legal cases involving asbestos-related diseases, particularly for women who developed mesothelioma due to environmental or non-occupational exposure. The findings support the following legal arguments:

  1. Causation Evidence: The study demonstrates a clear link between environmental asbestos exposure and mesothelioma in women, providing scientific evidence to support claims of causation.
  2. Occupational and Environmental Exposure Pathways: While most asbestos-related cases focus on occupational exposure, this study highlights the significant risks of environmental exposure, such as living near asbestos mines or factories. This is crucial for cases where women were exposed outside traditional industrial settings.
  3. Counterarguments to Defense Claims: The study’s findings counter common defense arguments that mesothelioma in women is unrelated to asbestos exposure. The elevated fiber burden of amphibole asbestos in women with mesothelioma strengthens claims of unrecognized or indirect exposure.
  4. Latency Periods: The research underscores the long latency periods associated with mesothelioma, which can help establish timelines for exposure and disease development in legal cases.

By providing robust scientific data, this study can be used to strengthen liability and compensation claims for women affected by asbestos exposure.

Occupation Groups at Risk
The study identifies several high-risk groups and scenarios where women may have been exposed to asbestos:

  • Residents Near Asbestos Mines or Factories: Women living within 2,000 meters of asbestos mines or manufacturing plants face a significantly increased risk of mesothelioma due to environmental exposure.
  • Household Exposure: Women exposed to asbestos fibers brought home on the clothing of family members working in asbestos-related industries.
  • Non-Industrial Environmental Exposure: Women in regions with naturally occurring asbestos or erionite, such as Karain Village in Turkey, are at heightened risk.
  • Occupational Exposure in Non-Traditional Roles: Although less common, women working in industries such as construction, shipbuilding, or manufacturing may also face occupational exposure.

These scenarios highlight the diverse ways women can be exposed to asbestos, emphasizing the need for legal representation to address these unique exposure pathways.

Current Medical Understanding
The study aligns with current medical knowledge, which recognizes asbestos exposure as the primary cause of mesothelioma. It reinforces the understanding that amphibole asbestos and erionite are highly carcinogenic, with significant risks even at environmental exposure levels. The findings also support the notion that women may retain more asbestos fibers due to physiological differences, such as lung size and breathing patterns. While the study does not delve into genetic or hormonal factors, it provides a strong foundation for further research into gender-specific risks.

Citation
Metintas, M., et al. (2002). Women and Mesothelioma. CHEST, 121(6), 2224.

National Library of Medicine Link
For additional details, visit the study on the National Library of Medicine: https://pubmed.ncbi.nlm.nih.gov/12475820/

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