Critical Review of Epidemiologic Studies Related to Ingested Asbestos - (1983)

Authors: G.M. Marsh

The Legal Implications of Ingested Asbestos: A Comprehensive Review of Epidemiologic Studies

Abstract The study, Critical Review of Epidemiologic Studies Related to Ingested Asbestos by Gary M. Marsh, published in Environmental Health Perspectives (1983), critically evaluates 13 epidemiologic studies conducted in five regions across the United States and Canada. These studies investigated the potential health risks of ingested asbestos, particularly its association with cancer mortality and incidence. The research identified possible links between asbestos in water supplies and cancers of the esophagus, stomach, pancreas, prostate, small intestine, and leukemia. However, significant methodological weaknesses in the studies prevented definitive conclusions about risk levels. A binomial probability analysis of eight independent studies suggested that the observed positive associations for certain cancers were unlikely to be due to chance, indicating a potential biological basis for the findings. The study also highlighted inconsistencies in patterns for pancreatic, kidney, and leukemia cancers compared to occupational asbestos exposure. These findings provide critical insights into the health risks of asbestos exposure and its implications for public health and legal accountability.


Legal Relevance This study offers valuable evidence for individuals pursuing asbestos-related legal claims. It underscores the potential health risks of asbestos exposure, even through ingestion, and provides a foundation for legal arguments in cases involving cancer diagnoses linked to asbestos-contaminated water supplies. Key legal takeaways include:

  1. Evidence Pathways: The study identifies specific cancers (e.g., esophagus, stomach, pancreas, and prostate) with statistically significant associations to ingested asbestos. This evidence can be used to establish causation in legal claims.

  2. Occupational History Relevance: The findings align with patterns observed in occupational asbestos exposure, reinforcing the importance of documenting exposure history. This is particularly relevant for individuals who worked in industries where asbestos-contaminated water was prevalent.

  3. Counterarguments to Defense Claims: While the study acknowledges methodological limitations, it emphasizes that the observed cancer associations are unlikely to be due to chance. This counters common defense arguments that dismiss asbestos-related claims due to insufficient evidence.

For individuals seeking compensation for asbestos-related illnesses, this study provides a robust scientific basis to support claims of negligence and liability.


Occupation Groups at Risk The study highlights several occupational groups and scenarios where individuals may have been exposed to asbestos-contaminated water, increasing their risk of developing asbestos-related diseases. These include:

  1. Industrial Workers: Employees in industries using asbestos-contaminated water for manufacturing processes faced prolonged exposure, increasing their risk of gastrointestinal cancers.

  2. Construction Workers: Workers involved in building projects using asbestos-cement pipes or materials were likely exposed to asbestos fibers through water supplies.

  3. Municipal Water Workers: Individuals responsible for maintaining or repairing asbestos-cement water pipes may have been exposed to asbestos fibers leaching into water systems.

  4. Miners and Mill Workers: Those working in asbestos mines or processing facilities may have ingested asbestos fibers through contaminated water sources near mining sites.

  5. Residents in Affected Areas: Communities serviced by water supplies containing asbestos fibers, particularly in regions studied (e.g., Puget Sound, Washington, and the Bay Area, California), are at risk of exposure.

These groups are at heightened risk due to their proximity to asbestos-contaminated water supplies, making them potential claimants in asbestos-related legal cases.


Current Medical Understanding The study aligns with current medical knowledge regarding asbestos exposure and its health risks. While inhalation of asbestos fibers is the primary cause of diseases like mesothelioma and asbestosis, ingested asbestos has also been implicated in gastrointestinal cancers. Modern research supports the study's findings that certain cancers, such as those of the stomach and esophagus, may have a biological basis linked to asbestos exposure. However, the study's acknowledgment of methodological limitations highlights the need for further research to establish definitive risk levels. This reinforces the importance of long-term monitoring and legal advocacy for affected individuals.


Citation Marsh, G. M. (1983). Critical review of epidemiologic studies related to ingested asbestos. Environmental Health Perspectives, 53, 49-56. https://doi.org/10.1289/ehp.835349. PMID: 6662094; PMCID: PMC1569098.
Access the study on the National Library of Medicine


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